Clinical Protocols
Applied science for lifespan extension. We document the specific dosing regimens, exercise prescriptions, and dietary frameworks utilized by leading longevity physicians.
Pharmacology
Rapamycin: Off-Label Dosing
An analysis of weekly pulsatile dosing vs daily dosing, managing mTORC1 inhibition while minimizing mTORC2 suppression to preserve metabolic health.
Exercise Physiology
Zone 2 Aerobic Base
The metabolic rationale for exercising precisely at the lactate threshold. Protocols for measuring wattage, heart rate, and perceived exertion.
Dietary
Protein Distribution for Sarcopenia
Why total daily protein is insufficient. Exploring the leucine threshold required per meal to trigger muscle protein synthesis in older adults.